Communicate with Supplier? Supplier
Jerry Mr. Jerry
What can I do for you?
Chat Now Contact Supplier

Shandong Chenyi Environmental Protection Technology Co.,Ltd

Products

Home > Products > Anticancer APIS > High quality AZD9291|Osimertinib Cas 1421373-65-0

High quality   AZD9291|Osimertinib Cas 1421373-65-0
High quality   AZD9291|Osimertinib Cas 1421373-65-0

High quality AZD9291|Osimertinib Cas 1421373-65-0

Payment Type: L/C,T/T,Paypal
Incoterm: FOB,CIF
Min. Order: 10 Gram
Delivery Time: 3 Days

Basic Info

    Model No.: Cas 1421373-65-0

Additional Info

    Packaging: 10g 100g 1kg

    Productivity: 100 kg/month

    Brand: cy

    Transportation: Ocean,Land,Air

    Place of Origin: China

    Supply Ability: 50kg

    Certificate: ISO 9001, GMP

    Port: QINGDAO,SHANGHAI

Product Description


Prodcut name

AZD9291/Osimertinib

Synonyms

N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide

MOQ

10G

CAS No.

1421373-65-0

Appearance

It is white or very slightly yellow,crystalline powder

Molecular Formula

C28H33N7O2

Molecular Weight

499.61

Assay

98.5%~101.5%

Application

Pharma grade or research purpose

Packing

As per your request

Storage

Preserve in tight,light-resistant containers in a cool place

Remarks

NA

Custom synthesis

Available

Supply Ability

150kg/month

AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. AZD 9291 is an irreversible inhibitor of epidermal growth factor receptor (EGFR) sensitizing and T790M resistance mutations (IC50s = 15-17 nM) while sparing the wild-type form of the receptor (IC50 = 480 nM). It binds the related IGF1R and hERG receptors with significantly reduced potency.



Osimertinib, also known as AZD-9291 and Mereletinib, is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. It inhibits both activating and resistant EGFR mutations while sparing the normal form of EGFR that is present in normal skin and gut cells, thereby reducing the side effects encountered with currently available medicines.


osimertinib mechanism of action

Looking for ideal Tagrisso Overall Survival Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the Osimertinib Mesylate Tablets are quality guaranteed. We are China Origin Factory of Osimertinib Fda. If you have any question, please feel free to contact us.

Product Categories : Anticancer APIS

Send Inquiry

Tel:86-0531-18560179988

Fax:

Mobile Phone:+8613561750134Contact me with Whatsapp

Email:Sales@chenyichemistry.com

Address:No.215 Beiyuan Main street,tianqiao District, Jinan, Shandong