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Home > Products > Anticancer APIS > PF-6463922 CAS 1454846-35-5 Lorlatinib

PF-6463922 CAS 1454846-35-5 Lorlatinib
PF-6463922 CAS 1454846-35-5 Lorlatinib

PF-6463922 CAS 1454846-35-5 Lorlatinib

Payment Type: L/C,T/T,Paypal
Incoterm: FOB,CIF
Min. Order: 10 Gram
Delivery Time: 3 Days

Basic Info

    Model No.: CAS 1454846-35-5

Additional Info

    Packaging: 10g 100g 1kg

    Productivity: 100 kg/month

    Brand: cy

    Transportation: Ocean,Land,Air

    Place of Origin: China

    Supply Ability: 50kg

    Certificate: ISO 9001, GMP

    Port: QINGDAO,SHANGHAI

Product Description

Loratinib, also known as PF-06463922, is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity. Upon administration, ALK/ROS1 inhibitor PF-06463922 binds to and inhibits both ALK and ROS1 kinases. The kinase inhibition leads to disruption of ALK- and ROS1-mediated signaling and eventually inhibits tumor cell growth in ALK- and ROS1-overexpressing tumor cells. In addition, PF-06463922 is able to cross the blood brain barrier.


Product name Loratinib
Cas 1454846-35-5
Synonyms Loratinib; PF0643922; PF 0643922; PF-0643922
Category Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Standard purity:>99%
Appearance Loratinib powder
Usage Loratinib has been used in trials studying the basic science and treatment of Non-small Cell Lung Cancer and anaplastic lymphoma kinase (ALK)-positive Non-Small Cell Lung Cancer (NSCLC) and ROS1-positive NSCLC.
Shelf life 2 years
Storage Loratinib should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.

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Product Categories : Anticancer APIS

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