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Home > Products > Hot sellers API > High Quality CAS 153439-40-8 / Fexofenadine hydrochloride with Best Price

High Quality CAS 153439-40-8 / Fexofenadine hydrochloride with Best Price

High Quality CAS 153439-40-8 / Fexofenadine hydrochloride with Best Price

Payment Type: L/C,T/T,Paypal
Incoterm: FOB,CIF
Min. Order: 1 Kilogram
Delivery Time: 2 Days

Basic Info

    Model No.: CAS 153439-40-8

    Appearance: White Powder

Additional Info

    Packaging: 1KG

    Productivity: 300 T/year

    Brand: cy

    Transportation: Ocean,Land,Air

    Place of Origin: China

    Supply Ability: 300 kg

    Certificate: ISO 9001, GMP

    Port: QINGDAO,SHANGHAI

Product Description

Treatment Children rhinitis drugs Fexofenadine Hydrochloride 153439-40-8

fexofenadine hydrochloride dosage


CAS 153439-40-8

Other Names:Fexofenadine HCL

MF:C32H39NO4 HCL
Type:Anti-Allergic Agents

Grade Standard:Medicine Grade

Usage:Animal Pharmaceuticals

Purity:99.0%

Appearance:White crystalline powder

Molecular weigh:538.13

Boiling point:526.2°C at 760 mmHg

Flash ( ing ) point:272.1°C

Specification:

PARAMETERS LIMITS RESULTS
Description whiter crystalline powder whiter crystalline powder
Solubility soluble in methanol and in Complies
dilute alkali solutions
Identification IR To Comply Complies
HPLC To Comply Complies
Melting range 191 to 198 Degree 192 to 196 Degree
Loss on drying Not more than 1.0% w/w 0.07% w/w
Chlorides 6.46 to 6.66% w/w 6.57% w/w
Residue on ignition Not more than 0.1% 0.04%
Heavy metals Not more than 20ppm Complies
Related substances(HPLC) Not more than 0.50% 0.21%
Total impurity Assay(HPLC) Not more than 1.00% 0.54%
Residual solvents (GC) 98.0 to 102.0% w/w 98.71% w/w
Isopropyl Alcohol Not more than 5000ppm 3727.50ppm
Ethyl Acetate Not more than 5000ppm 764.79ppm
Particle Size (Malvern) 90% less than 100 Complies

Function:

Fexofenadine hydrochloride (trade name: Allegra) belongs to a second-generation antihistamine pharmaceutical drug. It is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. It is a kind of selectively peripheral H1 blocker. Its mechanism of action in vivo is through preventing the histamine-mediated activation of the H1 receptors, thus alleviating the symptoms related to allergy. Compared to the first-generation antihistamine drug, it is less prone to penetrate the blood-brain barrier, reducing the possibility to cause side effects such as drowsiness.

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